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Systemic Radiation Therapy Group

Faculty of Medicine / Department of Clinical Sciences, Lund / Section I / Radiation therapy

Visiting address: Universitetssjukhuset, 22184 Lund

Systemic Radiation Therapy Group's profile in Lund University Research portal

Description

The main research area of the group is systemic treatment of metastasized cancer using therapeutic radionuclides. To optimize dose delivery to tumor cells, radionuclides are conjugated to tracer molecules, e.g. antibodies or antibody fragments, targeting cancer-specific epitopes. Preclinical evaluation of treatment combinations and strategies aim to improve treatment efficacy. Multimodality imaging such as SPECT/PET/CT, and Cerenkov and Bioluminescence Imaging are also employed to evaluate tracer biokinetics, biological effects and properties such as tumor uptake and penetration. Improving micro- and macro-scale dosimetry models and apply them using input from e.g. imaging modalities is another key aim. The group combines basic research with translational efforts, aiming to implement novel radionuclide therapies in the clinic. The current focus is on prostate cancer radioimmunotherapy targeting human kallikrein-related peptidase 2 (hK2), following promising preclinical results.

Staff

C

  • Jens Ceder

    Research project participant

    jens [dot] ceder [at] med [dot] lu [dot] se

R

  • Daniel Roth

    Research project participant

    daniel [dot] roth [at] med [dot] lu [dot] se

S

  • Anna Stenvall

    Research project participant

    anna [dot] stenvall [at] med [dot] lu [dot] se

  • Sven-Erik Strand

    Project manager

    sven-erik [dot] strand [at] med [dot] lu [dot] se

V

Z

  • Wahed Zedan

    Research project participant

    wahed [dot] zedan [at] med [dot] lu [dot] se

Ö

  • Anders Örbom

    Research project participant

    anders [dot] orbom [at] med [dot] lu [dot] se